Georgia O'Keeffe lived and worked in Abiquiú, New Mexico, after leaving New York.
O'Keeffe moved permanently from New York to New Mexico in 1949, three years after the death of her husband, Alfred Stieglitz. She divided her time between her Abiquiú home and studio and her residence at Ghost Ranch, both in northern New Mexico.
Abiquiú supplied architectural and landscape subjects that became central to her later work. The town is distinct from Taos, another famous New Mexico art center, and from Santa Fe, where O'Keeffe’s museum was later established.
The most precise answer is Abiquiú, rather than the broader region of New Mexico. Her relationship with the state began much earlier, but permanent residence came in 1949, when she made the landscape and buildings of northern New Mexico the center of her daily life.