In which historical setting does Assassin's Creed III primarily take place?

Assassin's Creed III primarily takes place during the American Revolution.

The game follows Ratonhnhaké:ton, a Mohawk Assassin commonly called Connor, as he becomes involved in the conflict between the colonial revolutionaries, the British, and other groups. Major events occur in Boston, New York, and the surrounding frontier during the late 18th century.

Historical figures such as George Washington, Benjamin Franklin, and Samuel Adams appear in the game. The story uses real events and people as a backdrop, while Connor's personal plot and the Assassin-Templar conflict are fictionalized. The game also includes naval missions and a modern-day storyline involving Desmond Miles.

The title is sometimes confused with Assassin's Creed Unity, which is set in Paris during the French Revolution. Assassin's Creed III instead focuses on the American Revolution and its North American setting, making Connor the series' first major protagonist from an Indigenous background.