In 50 First Dates, Henry Roth lives and works on the Hawaiian island of Oahu.
Henry, played by Adam Sandler, is a marine veterinarian at Sea Life Park on Oahu. He falls in love with Lucy Whitmore, played by Drew Barrymore, but she has anterograde amnesia and forgets each day's events after a previous accident.
The film uses Oahu as both its setting and a major part of its visual identity. Locations associated with the story include Sea Life Park and parts of the island's coastline. Henry must create a new introduction to Lucy each day, producing the romantic comedy's repeating premise.
50 First Dates was released in 2004 and directed by Peter Segal. Although the story is fictional, its depiction of memory loss is a simplified romantic-comedy device rather than a detailed medical account of a specific real condition.