In Pixar's Cars 2, John Lasseter directs Lightning McQueen and Mater's international adventure.
Lasseter co-directed the film with Brad Lewis. The story expands the Cars setting beyond Radiator Springs, sending the characters to races and espionage-related events in locations including Tokyo, Porto Corso, and London. Mater becomes involved in an international mystery after being mistaken for an American agent.
Lasseter had directed the original Cars and was one of Pixar's central creative leaders. His return helped preserve the characters and visual world while the sequel shifted toward a globe-trotting spy-comedy structure. Brad Lewis, who had produced Ratatouille, shared directing duties on the sequel.
Brad Bird is sometimes selected because he directed another Pixar film, The Incredibles. Pete Docter and Andrew Stanton are also major Pixar directors, but they did not direct Cars 2. This question concerns the film's director, not the voice cast or fictional spy organization.