London is the main setting of the Frye twins' story in Assassin's Creed Syndicate.
Jacob and Evie Frye are twin Assassins who arrive in London in 1868, during the Industrial Revolution. The city is controlled by Templar influence and criminal gangs, so the twins build an underground network to challenge that power. Their missions take them through districts shaped by factories, railways, overcrowding, and rapid technological change.
Syndicate's London includes historical figures such as Queen Victoria, Charles Dickens, Charles Darwin, Florence Nightingale, and Alexander Graham Bell. The game divides the city into districts including Westminster, the City of London, Whitechapel, Southwark, and Lambeth. These districts are fictionalized versions of real Victorian London locations.
Jacob is generally associated with direct action and gang leadership, while Evie focuses more on stealth and the search for an important Piece of Eden. Although the twins share the same setting, they have distinct missions and personalities, making London both a historical backdrop and a major part of the game's identity.