In Assassin's Creed Origins, the game's primary historical setting is ancient Egypt.
The story follows Bayek of Siwa, a Medjay who investigates a conspiracy during the final years of Ptolemaic Egypt. The game depicts places such as Siwa, Alexandria, Memphis, and Cyrene, combining Egyptian traditions with Greek and Roman political influence.
Origins is set around the first century BCE, before the formal Assassin Brotherhood shown in earlier games. Its narrative presents the founding of the Hidden Ones, the organization that later develops into the Assassins. Ancient Greece is the setting of Assassin's Creed Odyssey, while medieval England is central to Assassin's Creed Valhalla. Origins also introduced a more extensive role-playing system and a large exploration-focused map.