Georgia O'Keeffe first exhibited at the New York gallery known as 291 in 1916.
The gallery's formal name was the Little Galleries of the Photo-Secession, but it became widely known by its street address, 291 Fifth Avenue. Alfred Stieglitz founded and operated it, using the space to show photography and European and American modern art.
O'Keeffe's charcoal abstractions were shown there in 1916 after Stieglitz received them from photographer and educator Anita Pollitzer. The exhibition introduced her work to New York's avant-garde art community and began her long professional association with Stieglitz.
291 closed in 1917, but Stieglitz continued promoting O'Keeffe through later galleries, including the Intimate Gallery and An American Place. Those later venues should not be confused with the gallery connected to her first New York exhibition.