Alfred Stieglitz first exhibited Georgia O'Keeffe's work at the gallery known as 291.
Stieglitz operated the gallery at 291 Fifth Avenue in New York City, originally called the Little Galleries of the Photo-Secession. It became widely known simply by its street number, 291.
In 1916, photographer Anita Pollitzer showed Stieglitz some of O'Keeffe's abstract charcoal drawings. Stieglitz was impressed and exhibited them at 291 without O'Keeffe's prior permission. The event began a professional relationship that profoundly shaped her public career.
The gallery was important beyond O'Keeffe: it introduced American audiences to European modernists including Picasso, Matisse, Cézanne, and Rodin. It closed in 1917, but Stieglitz continued presenting O'Keeffe's work at later galleries.