Who voiced the villain Syndrome?

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Who voiced the villain Syndrome? Jason Lee voiced Syndrome in Pixar’s The Incredibles.

Syndrome is the villainous identity of Buddy Pine, a brilliant boy who once idolized Mr. Incredible and called himself IncrediBoy. After Mr. Incredible rejects his offer to become a sidekick, Buddy turns his scientific talent toward revenge. As an adult, he becomes Syndrome and uses advanced technology rather than innate superpowers.

Jason Lee’s performance gives Syndrome a fast-talking, smug, and increasingly menacing personality. Lee was best known at the time for live-action roles, including Earl Hickey in My Name Is Earl, making the animated villain a notable part of his voice-acting work.

A common mix-up is assigning the role to Craig T. Nelson, who voiced Mr. Incredible, or Samuel L. Jackson, who voiced Frozone. Brad Bird, the film’s writer-director, voiced Edna Mode—not Syndrome. Syndrome’s civilian name is Buddy Pine, while his villain name reflects his obsession with proving that technology can rival superpowers.

Source: Wikipedia · fact-checked Sept. 2026

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