Who played Dr. Lisa Cuddy, the administrator who oversees House, in House M.D.?

Lisa Edelstein played Dr. Lisa Cuddy, the administrator who oversees Gregory House, in House M.D.

Cuddy is the Dean of Medicine and hospital administrator at Princeton-Plainsboro Teaching Hospital. She values House’s diagnostic brilliance but regularly confronts his rule-breaking, dangerous experiments, and disregard for hospital policy. Her authority creates a continuing conflict between clinical results and institutional responsibility.

Edelstein appeared as a series regular for the first seven seasons. Cuddy’s professional relationship with House eventually develops into a romantic storyline, adding personal stakes to their arguments. Viewers sometimes confuse Edelstein with Jennifer Morrison, who played immunologist Allison Cameron, or Olivia Wilde, who played physician Remy “Thirteen” Hadley.