Who played Dr. Lisa Cuddy, House’s hospital boss, in House M.D.?

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Lisa Edelstein played Dr. Lisa Cuddy, House’s hospital boss, in House M.D. Cuddy is the dean of medicine and administrator responsible for managing House’s difficult conduct and extraordinary diagnostic results.

Cuddy’s position places her between institutional responsibilities and House’s unconventional methods. She frequently disciplines him, negotiates with him, or protects his department when his medical successes justify the risks he takes. The series also develops a complicated personal relationship between Cuddy and House, making their professional arguments part of a longer character story.

Edelstein joined the main cast from the start and remained a central figure for much of the series. Cuddy is sometimes confused with Cameron or Thirteen because all are prominent women doctors, but their jobs differ: Cuddy is an administrator, while Cameron and Thirteen work as physicians on diagnostic teams. Edelstein left the regular cast after the show’s seventh season.

Source: Wikipedia · fact-checked Oct. 2026

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