The goddess of motherhood, magic, and fertility in ancient Egyptian religion is Isis.
Isis was a major Egyptian goddess whose powers combined maternal protection, healing magic, fertility, and care for the dead. In the Osiris myth, she searches for and restores the body of her murdered husband, Osiris. She then gives birth to Horus and protects him from danger while he grows up to challenge Set for the throne. These stories established Isis as an ideal mother and a powerful magician.
Her maternal role extended beyond royal mythology. Egyptians invoked Isis in healing spells and childbirth, especially because she was believed to have protected Horus from snakes, scorpions, and illness. She also helped the dead, following the example of her restoration of Osiris. In later periods, her worship spread through the Greek and Roman worlds, where she absorbed attributes from several other goddesses.
Isis is sometimes confused with Hathor, who was also connected with motherhood, fertility, femininity, and royal power. Sekhmet was primarily a fierce goddess of warfare and plague, while Bastet was associated with protection, domestic life, and cats. Isis’s distinctive combination of motherhood and magic makes her the best answer here.