House M.D. ended its television broadcast run in 2012.
The series finale, “Everybody Dies,” aired on May 21, 2012, bringing the eight-season drama to a close. The show had premiered nearly eight years earlier, on November 16, 2004.
By its final season, the series had undergone major cast and story changes while retaining Gregory House as its central character. The concluding storyline emphasized House's friendship with James Wilson and forced House to confront the consequences of his choices.
The 2012 finale ended the original television series; it was not a temporary season break. House M.D. therefore belongs to the group of major 2000s television dramas whose complete run spans the late 2000s and early 2010s. Its episodes continue to be distributed internationally and through later home-media and streaming releases.