Which two specialties does Gregory House practice in House M.D.?

Gregory House practices nephrology and infectious disease in House M.D.

Nephrology is the medical specialty devoted to the kidneys, while infectious disease focuses on illnesses caused by bacteria, viruses, fungi, parasites, and other infectious agents. The combination helps explain House’s role as a diagnostician who investigates complex, multisystem cases.

House leads the Department of Diagnostic Medicine at Princeton-Plainsboro Teaching Hospital. His team often draws on specialists from other departments, but House’s own expertise guides the differential diagnosis and the search for rare causes.

Viewers sometimes identify House simply as a neurologist or general physician because his cases involve many organs and symptoms. He is not presented as a surgeon, and the show’s diagnostic department is fictionalized for drama. His medical license and employment status also change during the series, but his established specialties remain nephrology and infectious disease.