Which two medical specialties does House practice in House M.D.?

In House M.D., Gregory House is certified in infectious disease and nephrology.

These specialties help explain the unusual range of cases handled by House’s diagnostic department. Infectious disease concerns illnesses caused by bacteria, viruses, fungi, and parasites, while nephrology focuses on the kidneys and related conditions such as electrolyte disorders and kidney failure.

House’s medical expertise is broader than those two formal specialties because the series presents him as an exceptional diagnostician. He frequently draws on neurology, immunology, toxicology, and other fields when solving cases. That broad knowledge is a storytelling device rather than a typical career path for one physician.

A common mix-up is calling House a neurologist because many episodes involve neurological symptoms. Another is confusing nephrology with urology: nephrology is primarily medical kidney care, whereas urology is a surgical specialty involving the urinary tract and reproductive system.