Which two medical specialties does Dr. Gregory House practice in House, M.D.?

Dr. Gregory House practices infectious disease and nephrology in House, M.D.

House’s specialties explain why his diagnostic work often involves complex systemic illnesses, unexplained infections, kidney disorders, and unusual interactions between organs. The show frequently presents him as a diagnostician who draws on many fields, but his formal medical background is in these two specialties.

Nephrology is the branch of medicine concerned with the kidneys and their diseases. Infectious disease focuses on illnesses caused by bacteria, viruses, fungi, parasites, and other infectious agents. Both fields can involve difficult cases in which symptoms appear in several parts of the body.

House’s fictional department is diagnostic medicine rather than a standard infectious-disease or nephrology clinic. That distinction sometimes causes viewers to list “diagnostician” as his specialty, but diagnostician describes his role, while the two named specialties describe his medical training.