Which pope issued the 1493 bull Inter caetera after Columbus's first voyage?

Which pope issued the 1493 bull Inter caetera after Columbus's first voyage? Pope Alexander VI issued it.

The bull was issued in May 1493 after news of Columbus's return reached Europe. Alexander VI, born Rodrigo Borgia, granted the Catholic Monarchs Ferdinand II of Aragon and Isabella I of Castile rights over lands west and south of a dividing line drawn about 100 leagues from the Azores or Cape Verde islands.

Inter caetera was part of a group of papal documents known as the Bulls of Donation. It aimed to support Castile's claims while encouraging Christian evangelization, but its wording and legal meaning were disputed from the beginning. Portugal objected that the arrangement threatened its earlier Atlantic claims.

The bull is often confused with the Treaty of Tordesillas. Inter caetera was a papal grant issued in 1493; the 1494 treaty was a direct agreement between Castile and Portugal that moved the demarcation line farther west, helping Portugal secure territory that later included Brazil.