Which Pokémon is numbered 150 in the National Pokédex?

Mewtwo is number 150 in the National Pokédex.

In the first-generation Pokédex sequence, Mewtwo follows Dragonite at number 149 and comes immediately before Mew at number 151. This placement reflects the story connection between the two Pokémon.

Mewtwo is described as a genetically engineered Pokémon created from Mew’s DNA. In Pokémon Red and Blue, the player learns about it through research documents in the ruined Pokémon Mansion on Cinnabar Island.

The original games place Mewtwo in Cerulean Cave, where it becomes available only after the player defeats the game’s final opponents. Because it is both rare and extremely powerful in the first-generation games, Mewtwo became one of the franchise’s most famous Legendary Pokémon.