Which Pokémon is number 150 in the National Pokédex?

Mewtwo is Pokémon number 150 in the National Pokédex.

It is one of the original Generation I species introduced in the 1996 Pokémon games. In National Pokédex order, Mewtwo appears immediately before Mew, which is number 151 and traditionally completes the original Pokédex sequence.

Mewtwo's story distinguishes it from most Pokémon. In the franchise's fiction, scientists created it from genetic material associated with Mew, making it an engineered Pokémon rather than a naturally discovered species. Its powerful psychic abilities and laboratory origin also made it central to the first Pokémon feature film.

A common mix-up is reversing Mewtwo and Mew because their names and origins are closely connected. The numerical order is clear: Mewtwo is 150, while Mew is 151. Later games expanded the National Pokédex far beyond the original 151, but these two numbers remain part of the series' foundational history.