Which medical specialties does Gregory House specialize in on House M.D.?

Gregory House specializes in infectious disease and nephrology in House M.D. These are his formal medical specialties, even though he leads a broader diagnostic department.

Infectious disease concerns illnesses caused by pathogens, while nephrology focuses on the kidneys and related disorders. The combination gives House expertise in systemic illnesses, unexplained fevers, kidney failure, electrolyte problems, and other conditions that can affect multiple organs.

Viewers sometimes identify House only as a diagnostician, because that is his department and the show’s central job. Others confuse his specialty with the specialties of his colleagues, such as oncology or intensive care. The series deliberately gives House a wide diagnostic role, but the stated specialty pairing remains infectious disease and nephrology.