The Overwatch map set on a road through the American Southwest with a diner is Route 66. The map takes its name and visual identity from the historic U.S. highway associated with desert landscapes, roadside businesses, and long-distance travel.
In the game, Route 66 is an Escort map. Attackers move a payload along a stylized stretch of highway while defenders try to stop it. Its scenery includes a roadside diner, a gas station, desert rock formations, and the abandoned-looking infrastructure of a frontier route. The setting blends recognizable Americana with Overwatch's futuristic world.
The real U.S. Route 66 was established in 1926 and originally ran from Chicago to Santa Monica, California. It crossed eight states and became known as the “Mother Road,” especially after its appearance in popular culture and literature. Blizzard's map is not a literal reconstruction of the entire highway; it is a fictionalized section inspired by its mythology.
The other choices use very different settings: Watchpoint: Gibraltar is a space-launch facility, Hollywood depicts a film studio, and Dorado is a Mexican city.