Which leg was injured in Gregory House’s infarction in House M.D.?

Gregory House’s infarction injured his right leg in House M.D.

Before the series begins, House suffers an infarction in the quadriceps muscle of his right leg. The damage leads to permanent muscle loss, chronic pain, and the limp for which the character is known. He eventually uses a cane and takes pain medication, especially Vicodin, to manage the consequences.

The show reveals the injury through flashbacks and later discussions rather than presenting it as a simple recent accident. House initially undergoes treatment that saves his life but leaves lasting damage. His pain and dependence on medication become major parts of his personal story and affect his relationships and medical decisions.

The injury is sometimes misremembered as affecting the left leg because House’s cane and posture can make the side difficult to track on screen. The established character history identifies the damaged leg as the right one.