Which leg is injured in Gregory House's limp in House M.D.?

Gregory House's limp in House M.D. affects his right leg. The character suffers permanent muscle damage after an infarction in the quadriceps muscle of that leg, leaving him with chronic pain and an altered gait.

House uses a cane and regularly takes Vicodin to manage the pain. The injury is not merely a visual character trait: it affects his mood, mobility, relationships, and dependence on medication throughout the series. The backstory also explains why House approaches pain and disability with unusual personal intensity.

The show presents the infarction and its consequences through flashbacks and later revelations. The cane is often associated with House's silhouette, so viewers may remember the prop without recalling the specific side. His right leg, rather than his left leg or both legs, is the injured limb identified in the character's biography.