Which House M.D. episode features House and Amber’s bus-crash mystery and aired as the season-four finale?

The story behind the answer

“Wilson’s Heart” is the House M.D. season-four finale about House and Amber’s bus-crash mystery.

The episode follows the consequences of the bus accident introduced in “House’s Head.” House has lost parts of his memory and works to reconstruct what happened, while Amber Volakis is found critically ill. The medical mystery becomes inseparable from Wilson’s personal life because Amber is Wilson’s partner.

“Wilson’s Heart” aired on May 19, 2008, and concludes the two-part storyline. The episode’s title emphasizes Wilson’s emotional crisis as he faces the possibility of losing Amber and struggles with House’s role in the events leading to the accident.

The episode is often confused with “House’s Head,” the preceding installment, because both concern the same crash and missing memories. “House’s Head” is the season-four penultimate episode; “Wilson’s Heart” is the finale. The pair is one of the show’s most prominent multi-episode arcs.

Source: Wikipedia · fact-checked Sept. 2026

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