Which Full House episode was the only one taped in San Francisco?

The only Full House episode taped in San Francisco was “Comet's Excellent Adventure.” It is the season-eight premiere and follows Comet after he runs away, sending the Tanner family around the city to find him.

Although the series was set in San Francisco, nearly all of it was filmed on soundstages in Southern California. The famous Victorian houses and other recognizable landmarks appeared mainly in the opening credits, which created a stronger sense of place than the regular production locations did.

This episode is often confused with “Tanner's Island,” because that season-three premiere was also filmed away from the usual studio. However, “Tanner's Island” was shot on location in Hawaii, not San Francisco. Full House also filmed the sixth-season finale at Walt Disney World.

The San Francisco setting remained central to the show's identity: Danny's television job, the Tanner home, and many story references were tied to the city even when the cameras were elsewhere.