Which fictional doctor is the main character of House M.D.?

Gregory House is the main fictional doctor in House M.D.

House is a diagnostician known for solving rare and difficult cases at Princeton-Plainsboro Teaching Hospital. His medical brilliance is paired with a hostile bedside manner, physical disability caused by an old leg injury, and dependence on the painkiller Vicodin during much of the series.

The character is portrayed by Hugh Laurie and was developed as a medical counterpart to Sherlock Holmes. The connection appears in details such as House’s deductive reasoning, his unconventional methods, and the parallel between James Wilson and Dr. Watson.

The other principal doctors are important but serve different roles. James Wilson is House’s oncologist friend, Eric Foreman becomes a neurologist and administrator, and Robert Chase is a member of House’s diagnostic teams. The title character’s full name is Gregory House, though colleagues usually call him House.