Which fictional character dies in the House M.D. season-four finale?

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Amber Volakis dies in the House M.D. season-four finale.

Amber, played by Anne Dudek, is one of the applicants competing for a place on House’s new diagnostic team. Her aggressive ambition earns her the nickname “Cutthroat Bitch,” but the character also develops a relationship with James Wilson.

In the two-part finale, Amber is seriously injured in a bus accident while accompanying an intoxicated House. She has taken amantadine, which cannot be removed from her system because of her kidney failure. The resulting poisoning leads to her death.

The character’s death is sometimes confused with the departure of other doctors from House’s teams. Amber’s storyline is especially important because it affects both Wilson and House and contributes to the series’ exploration of memory, guilt, and friendship.

Source: Wikipedia · fact-checked Oct. 2026

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