Which fictional address does House use as his home address in House M.D.?

House uses 221B Baker Street as his fictional home address in House M.D.

The address is a direct reference to 221B Baker Street, the London residence traditionally associated with Sherlock Holmes. House was deliberately modeled in part on Holmes: both characters are exceptionally observant, solve mysteries through deduction, and maintain complicated relationships with a loyal friend who helps connect them to ordinary social life.

In the series, House’s apartment is in Princeton, New Jersey, so the address functions as an in-universe joke and an out-of-universe clue to the character’s literary inspiration. It does not mean that House lives in London or that the medical drama is set in Britain.

The detail is easy to miss because the address is a reference rather than a major plot point. It is also distinct from 221A Baker Street, a different fictionalized address sometimes used in adaptations or mistaken recollections of the Holmes canon.