Gregory House is the director of diagnostic medicine at Princeton-Plainsboro Teaching Hospital in House M.D. His department handles rare and difficult cases that have resisted more routine diagnoses.
House is portrayed as a medical genius with expertise in infectious disease, nephrology, and diagnostic reasoning. He leads a small team of physicians who gather evidence, conduct tests, and revise hypotheses as each patient’s condition changes.
The character is played by Hugh Laurie and is loosely modeled on Sherlock Holmes, including the detective’s analytical methods and complicated relationship with a close friend. Viewers sometimes confuse House’s title with that of James Wilson, who heads oncology, or Lisa Cuddy, who serves as the hospital’s dean of medicine and administrator.