Which character in House M.D. is diagnosed with Huntington’s disease?

Remy “Thirteen” Hadley is diagnosed with Huntington’s disease in House M.D.

Thirteen learns that she carries the Huntington’s disease mutation after genetic testing. Huntington’s is an inherited neurodegenerative disorder caused by a mutation in the HTT gene. It can affect movement, cognition, and mood, and symptoms commonly emerge in adulthood, although the timing varies.

The diagnosis gives Thirteen a continuing personal conflict: she knows she is likely to develop a progressive illness but cannot predict exactly when it will become symptomatic. Her mother’s illness and her decisions about relationships, testing, and medical aid in dying are addressed in later storylines.

The fictional diagnosis is sometimes confused with other serious conditions shown in the series. Amber Volakis dies from complications involving amantadine toxicity after a bus accident, while James Wilson is diagnosed with thymoma. Thirteen’s Huntington’s diagnosis is specifically established through genetic testing and remains part of her character history.