Lisa Cuddy became House's boss as the hospital administrator in House M.D.
Lisa Cuddy, played by Lisa Edelstein, is the dean of medicine and hospital administrator at Princeton-Plainsboro Teaching Hospital. She supervises House, protects the institution from his rule-breaking, and simultaneously recognizes that his unusual methods can produce lifesaving diagnoses.
Cuddy and House have a complicated professional and personal relationship. Their arguments often concern patient safety, hospital policy, and House's conduct, while later seasons develop a romantic storyline between them. Cuddy's role also places her among the show's most important authority figures.
The character is sometimes confused with James Wilson because both are senior physicians who know House well. Wilson is an oncologist and friend; Cuddy is the administrator responsible for the hospital's medical operations. Cuddy leaves the series near the end of season seven, and Edelstein does not appear as a regular in season eight.