Which actor played Gregory House in the television series House M.D.?

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Hugh Laurie played Gregory House in the television series House M.D. His performance made the character—an exceptionally gifted but difficult diagnostician—one of the defining television doctors of the 2000s.

Laurie is an English actor, musician, and writer. Before House M.D., he was widely known in the United Kingdom for comedy, especially his work with Stephen Fry in A Bit of Fry & Laurie and Jeeves and Wooster. House therefore marked a major international dramatic breakthrough for him.

The role required Laurie to perform with an American accent, despite being British. He also portrayed House’s chronic leg pain and dependence on a cane, physical details central to the character’s history. Laurie won two Golden Globe Awards for the role and received multiple Emmy nominations.

Robert Sean Leonard, Omar Epps, and Jesse Spencer were also important cast members, but they played James Wilson, Eric Foreman, and Robert Chase respectively. None portrayed Gregory House.

Source: Wikipedia · fact-checked Sept. 2026

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