Which actor played Dr. Lisa Cuddy in House M.D.?

Lisa Edelstein played Dr. Lisa Cuddy in House M.D.

Cuddy is the dean of medicine and administrator at Princeton-Plainsboro Teaching Hospital. Her responsibilities include managing the hospital, supervising physicians, and repeatedly confronting House over his risky methods, rule-breaking, and unpredictable behavior.

Edelstein portrayed Cuddy from the beginning of the series through season seven. The character’s professional authority created an ongoing conflict with House, who often ignored institutional procedures while producing impressive diagnostic results. Their relationship also developed beyond workplace arguments during the series.

Cuddy was written as a highly capable physician and administrator rather than simply as House’s supervisor. Her storylines addressed leadership, motherhood, medical ethics, and the difficulty of balancing personal relationships with hospital responsibility. Edelstein’s performance made Cuddy one of the show’s best-known supporting characters.