The 2012 romantic drama starring Channing Tatum and Rachel McAdams is The Vow.
Directed by Michael Sucsy, the film follows newlyweds Leo and Paige Collins after a car crash leaves Paige with severe memory loss. She remembers her life before Leo, but not their relationship or marriage, forcing Leo to try to rebuild their connection.
The story was loosely inspired by Kim and Krickitt Carpenter, whose real-life marriage faced a similar crisis after Krickitt suffered a traumatic brain injury. The film changes many details and heightens the romance for dramatic effect, so it should not be treated as a precise retelling.
A common mix-up is The Notebook, another romantic drama associated with Rachel McAdams. That 2004 film pairs her with Ryan Gosling, while The Vow pairs her with Channing Tatum.