Which 2012 episode served as the House M.D. series finale?

“Everybody Dies” served as the House M.D. series finale in 2012. It is the second part of a two-part conclusion, following “Holding On” in the final season.

The finale centers on House facing a serious personal and legal crisis while the series revisits people and ideas from his life. Its title echoes the show's recurring focus on mortality, but the episode also emphasizes friendship, responsibility, and the possibility of change.

The episode aired on May 21, 2012, concluding an eight-season run. “Help Me” was the seventh-season finale, “Broken” was a two-part season-six premiere, and “House's Head” was part of a season-four storyline. Those titles are important House M.D. episodes, but they are not the series finale.