When did the medical drama House M.D. first premiere on Fox?

House M.D. first premiered on Fox on November 16, 2004. The episode was the pilot, introducing the brilliant but abrasive diagnostician Gregory House and his team at the fictional Princeton-Plainsboro Teaching Hospital.

The series was created by David Shore and developed with executive producer Katie Jacobs and director Bryan Singer. Its central format combined difficult medical mysteries with the personal conflicts created by House’s unconventional methods and dependence on pain medication.

House began as a mid-November launch rather than a traditional autumn premiere. It quickly became one of Fox’s signature dramas, eventually running for eight seasons. The show’s first episode is sometimes confused with its production or filming dates, but the broadcast premiere date is the one used for the series’ official debut.

The premiere date also helps distinguish House from later medical dramas influenced by it. The series remained on Fox until its finale in 2012, giving it a long network run for a show centered on rare diagnoses.