When did House M.D. premiere on Fox in the United States?

House M.D. premiered on Fox in the United States on November 16, 2004.

The first episode introduced Dr. Gregory House and his diagnostic team at the fictional Princeton-Plainsboro Teaching Hospital. The pilot established the series’ central format: a difficult medical mystery investigated through testing, argument, and differential diagnosis.

The premiere aired during Fox’s 2004–05 television season. Its success led the network to order a full season and helped establish the program as a major medical drama rather than a conventional hospital soap opera.

The date is often confused with later international broadcasts, which had different schedules. It is also distinct from the show’s final U.S. broadcast in 2012. House M.D. ultimately ran for eight seasons.