When did House M.D. first premiere in the United States?

House M.D. first premiered in the United States on November 16, 2004.

Fox broadcast the medical drama’s pilot in the network’s 2004–05 television season. The series introduced Hugh Laurie as Dr. Gregory House, a diagnostician whose unconventional methods and abrasive personality became its defining features.

The premiere established the show’s recurring format: a puzzling patient case, a diagnostic team testing competing theories, and House challenging both medical assumptions and hospital authority. Although the program was fictional, its cases were built around recognizable medical concepts and rare-disease puzzles.

The date is sometimes confused with the show’s later international premieres or with the 2012 broadcast of its finale. November 16, 2004 is the original U.S. premiere date, while the series concluded after eight seasons in May 2012.