What was House’s home address in House M.D.?

House’s home address in House M.D. is 221B Baker Street.

The address is a direct reference to Sherlock Holmes, whose fictional London home is 221B Baker Street. House was intentionally designed with several Holmes parallels: both characters are exceptionally observant, use deduction to solve mysteries, resist ordinary social conventions, and have a loyal friend named Wilson or Watson in the corresponding role.

In the series, House lives in apartment 221B Baker Street in Princeton, New Jersey, rather than in London. The address appears as part of the show’s character construction, signaling that medical diagnosis will be treated like detective work. House’s first name also echoes Holmes’s surname through the shared “Holmesian” inspiration.

The detail is sometimes misremembered as a real Princeton address. It is fictional within the program and primarily functions as an allusion to Arthur Conan Doyle’s detective stories.