House M.D.’s original U.S. television network was Fox.
Fox premiered the series in November 2004 and broadcast it throughout its eight-season run. The network’s schedule helped make the program a major national hit, particularly because the show combined a medical procedural format with a highly distinctive central character.
The program was produced for Fox by a group that included Heel and Toe Films, Shore Z Productions, and Bad Hat Harry Productions, with Universal Media Studios involved in distribution and production arrangements. The network’s branding is therefore different from the production companies credited on the series.
International viewers may associate House M.D. with other broadcasters because local networks and streaming services carried it in different territories. Those later outlets did not change the answer to this question: Fox was the original U.S. network. The show’s first episode aired in 2004, and its final broadcast on Fox came in 2012.