What street address does Gregory House use in House M.D.?

Gregory House uses the address 221B Baker Street in House M.D.

The address is a deliberate reference to Sherlock Holmes, who famously lives at 221B Baker Street in Arthur Conan Doyle’s stories. House’s name, investigative method, drug use, musical talent, and friendship with James Wilson also parallel elements of Holmes and Dr. Watson.

In the series, 221B is House’s apartment address in Princeton, New Jersey, rather than a claim that he lives in London. The reference functions as an Easter egg and signals the detective-story structure beneath the medical plots: symptoms are clues, patients can hide information, and House searches for the explanation that fits the evidence.

The address is often written as “221B Baker Street,” with the letter B identifying the apartment or unit. It should not be confused with House’s hospital office or Wilson’s neighboring apartment.