What street address does Gregory House have in House M.D.?

Gregory House’s address in House M.D. is 221B Baker Street.

The address is a direct reference to Sherlock Holmes, who famously lives at 221B Baker Street in Arthur Conan Doyle’s stories. House is designed as a modern medical detective, and the series repeatedly parallels him with Holmes through their names, deductive methods, musical interests, and reliance on a loyal friend.

In the show, House’s apartment is in Princeton, New Jersey, not London. That difference can cause confusion because the address is deliberately borrowed from the fictional detective’s London home. The reference is therefore symbolic rather than a claim that House lives in the original Baker Street setting.