What specialty department does Gregory House lead in House M.D.?

Gregory House leads the Diagnostic Medicine department in House M.D. His team is brought in when patients have unusual, complicated, or unexplained illnesses that other departments have not solved.

Diagnostic Medicine gives the series its distinctive structure. House and his fellows form hypotheses, order tests, observe symptoms, and repeatedly revise their conclusions. The work resembles a medical version of detective fiction, with the final diagnosis often emerging only after several plausible explanations fail.

The department should not be confused with House’s own medical specialties. House is specifically described as a specialist in infectious disease and nephrology, while Diagnostic Medicine is the hospital department he directs. Neurology, oncology, and cardiology are separate specialties represented by other recurring doctors.