What Sherlock Holmes address is associated with House's apartment in House M.D.?
Answer
221B Baker Street
House's apartment in House M.D. is associated with the Sherlock Holmes address 221B Baker Street.
The connection reflects the show's deliberate inspiration from Arthur Conan Doyle's detective stories. Gregory House parallels Holmes through his unusual intelligence, deductive reasoning, drug dependence, musical ability, and tendency to disregard ordinary social rules.
House's friend James Wilson parallels Dr. Watson in the broad structure of the relationship: he is a trusted companion who helps interpret House's behavior and remains close despite House's difficult personality. The series also adapts other Holmes-like names and ideas in selected storylines.
The address is not meant to suggest that House literally lives in London. House M.D. is set mainly in New Jersey, and the Baker Street reference is an allusion to the fictional detective's London home. The correct canonical Holmes address is 221B, not 221A.