In House M.D., Gregory House practices nephrology alongside infectious disease medicine. Nephrology is the medical specialty concerned with the kidneys, kidney function, and related disorders.
The show's premise places House in charge of a diagnostic team rather than presenting him as a conventional single-specialty consultant. His combined background helps explain why he can approach cases involving systemic illness, unusual infections, organ failure, and complex laboratory findings.
House's specialty is sometimes confused with neurology because the series frequently presents puzzling symptoms involving the brain, behavior, or movement. However, the character is not primarily a neurologist. The show identifies him as a board-certified diagnostician with specialties in infectious disease and nephrology.