What medical specialty does Gregory House head in House M.D.?

Gregory House heads the Department of Diagnostic Medicine in House M.D. His specialty is diagnosing complex cases that other departments have been unable to explain.

The department is fictionalized as a small, highly specialized unit at Princeton-Plainsboro Teaching Hospital. House works with a rotating group of doctors, assigning tests and proposing differential diagnoses while challenging assumptions made by other physicians. The cases often cross several medical specialties, which is why the team consults experts throughout the hospital.

House is also described as having expertise in nephrology and infectious disease, but those are not the name of the department he leads. That distinction causes a common mix-up: his personal medical background differs from the formal hospital unit responsible for the show’s central diagnostic cases.