What medical specialties does Dr. House lead in House M.D.?

Dr. House leads the diagnostic medicine department in House M.D.

The department handles cases that other doctors have been unable to explain. House’s team gathers a detailed history, proposes differential diagnoses, orders targeted tests, and revises its theories as new evidence appears. This structure turns medical investigation into the show’s central mystery format.

The series sometimes describes House as a specialist in both infectious disease and nephrology. Those are his medical specialties, but they are not the name of the hospital department he directs. The department is Diagnostic Medicine, and its work is broader than either specialty alone.

That distinction matters because the team treats patients with neurological, autoimmune, infectious, metabolic, and other conditions. House’s expertise is presented as unusually wide, while his formal department exists specifically for puzzling cases. The answer is therefore diagnostic medicine, rather than nephrology or infectious disease.