Hugh Laurie plays Dr. Gregory House in House M.D.
Gregory House is the series’ central character: a highly gifted diagnostician known for solving rare and complicated medical cases. He works at the fictional Princeton-Plainsboro Teaching Hospital and often approaches patients and colleagues with bluntness, sarcasm, and skepticism.
House is also characterized by chronic pain in his right leg and dependence on Vicodin, a prescription painkiller. These elements are important to his character but do not replace the show’s focus on diagnostic reasoning and medical uncertainty.
The character was deliberately modeled in part on Sherlock Holmes. Both figures use observation and deduction, live with complicated personal habits, and have a close friend whose surname begins with “Wilson” in House’s case. Hugh Laurie played House throughout all eight seasons.