What is the surname of House M.D.'s oncologist and Gregory House's best friend?

The story behind the answer

Wilson is the surname of House M.D.'s oncologist and Gregory House's best friend, Dr. James Wilson.

James Wilson heads the oncology department at Princeton-Plainsboro Teaching Hospital. His medical work involves cancer patients, while his personal storyline is closely connected to House's decisions and behavior.

Wilson often acts as House's moral counterweight. He understands House's intelligence and loyalty but is also willing to criticize his selfishness, manipulation, and disregard for rules. Their friendship survives repeated professional and personal crises across the series.

The surname is easy to confuse with Foreman, Taub, or Chase because all are prominent doctors at the same hospital. Foreman is the neurologist, Taub is a plastic surgeon, and Chase is an intensivist who later becomes a diagnostician. Wilson specifically identifies the oncology chief played by Robert Sean Leonard.

Source: Wikipedia · fact-checked Sept. 2026

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