The surname of Gregory, the central diagnostician in House, M.D., is House.
Dr. Gregory House is the series protagonist and heads the fictional Department of Diagnostic Medicine at Princeton-Plainsboro Teaching Hospital. He is portrayed as exceptionally skilled at recognizing unusual disease patterns, but his methods and personal conduct frequently create conflicts with colleagues.
The character's name is also part of the show's wordplay and literary design. His surname resembles “Holmes,” the surname of Sherlock Holmes, and several elements of House's characterization echo that detective. The series also gives House a close friend, James Wilson, whose role parallels the observing companion associated with Holmes stories.
“House” can be confused with the show's title, the hospital setting, or the actor Hugh Laurie. The answer here is the character's surname, not the actor's name or the title of the program.